The Genizer Jacketed Liposome Extruders are compressed air-driven and temperature-controlled, suitable for applications ranging from testing to manufacturing liposomes and lipopolyplexes for drug and gene delivery. They allow for the rapid and easy production of homogeneous samples in minutes, typically requiring only 5-10 passes to achieve uniform liposome size. These extruders are specifically designed to create homogeneous unilamellar liposomes and lipopolyplexes through a one-step extrusion process. This process involves forcing lipid suspensions containing drugs, proteins, or genes through track-etched filters with defined pore sizes. The procedure is relatively gentle, using moderate pressures up to 500 psi at controlled temperatures. The Genizer Jacketed Extruder features virtually no dead volume, is easy to clean, suitable for sterilization, and complies with FDA and GMP sanitary standards for pharmaceuticals.